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Invitrogen™ Phospho-DNAJC2 (Ser49) Polyclonal Antibody
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Catalog No. PIPA5105692
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PIPA5105692 100 μL
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Catalog No. PIPA5105692 Supplier Invitrogen™ Supplier No. PA5105692
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of DNAJC2/MPP11 only when phosphorylated at Ser49.

EIF4EBP1 is one member of a family of translation repressor proteins. It directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-DNAJC2 (Ser49)
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Dnajc2
Gene Accession No. P54103, Q99543
Gene Alias (rat homolog) mouse id-associated protein 1; AU020218; DnaJ (Hsp40) homolog, subfamily C, member 2; DnaJ heat shock protein family (Hsp40) member C2; dnaJ homolog subfamily C member 2; DnaJ homolog subfamily C member 2, N-terminally processed; Dnajc2; Gliosarcoma-related antigen MIDA1; Id associate 1; Mida1; Mouse Id associate 1; M-phase phosphoprotein 11; MPHOSPH11; MPP11; Unknown (protein for MGC:139161); ZRF1; Zrf2; ZUO1; zuotin related factor 1; zuotin related factor 2; zuotin-related factor 1
Gene Symbols Dnajc2
Host Species Rabbit
Immunogen A synthesized peptide derived from human DNAJC2(Accession Q99543), corresponding to amino acid residues around phosphorylated Ser49.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22791, 27000
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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