Phospho-DRP1 (Ser616) Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-2382	100 μL

Catalog No. 50-198-2382 Supplier Bioss Supplier No. BS12702R

Description

Rabbit Polyclonal Antibody

Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis. Their continued expression in areas of high synaptic remodeling such as the cerebellum, hippocampus, and the olfactory system suggests that these proteins may also be involved in adult brain plasticity. CRMP-1 was initially identified as a dihydro-pyrimidinase expressed exclusively in brain; later studies have shown that it is involved with neurotrophin (NT) 3-induced neurite formation and outgrowth. CRMP-1 localization switches from axonal to somatodendritic when neurons reach functional maturity, suggesting that it is involved in early neuronal differentiation as well as in later processes related to the survival or death of the newly generated neurons.

Specifications

• Antigen: Phospho-DRP1 (Ser616)
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: CRMP1
• Gene Accession No.: Q14194
• Gene Alias: Collapsin response mediator protein 1; CRMP1; CRMP-1; dihydropyrimidinase-like 1; Dihydropyrimidinase-related protein 1; DPYSL1; DRP1; DRP-1; Ulip3; ULIP-3; Unc-33-like phosphoprotein 3
• Gene Symbols: CRMP1
• Host Species: Rabbit
• Immunogen: KLH conjugated synthesised phosphopeptide derived from human DRP1 around the phosphorylation site of Ser616.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1400
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG