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Invitrogen™ Phospho-DUSP16 (Ser446) Polyclonal Antibody
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Catalog No. PIPA5106012
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PIPA5106012 100 μL
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Catalog No. PIPA5106012 Supplier Invitrogen™ Supplier No. PA5106012
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of DUSP16 only when phosphorylated at Ser446.

Dual-specificity phosphatases constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP16 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK proteins ERK, JNK, and p38 with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25-like domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-DUSP16 (Ser446)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene DUSP16
Gene Accession No. Q9BY84
Gene Alias 3830417M17Rik; AW558566; D6Ertd213e; dual specificity phosphatase 16; dual specificity protein phosphatase 16; Dusp16; KIAA1700; MAP kinase phosphatase 7; MAP kinase phosphatase-7; map kinase phosphatase-M; MAPK phosphatase-7; MGC129701; MGC129702; mitogen-activated protein kinase phosphatase 7; Mkp7; MKP-7; Mkpm
Gene Symbols DUSP16
Host Species Rabbit
Immunogen A synthesized peptide derived from human DUSP16(Accession Q9BY84), corresponding to amino acid residues around phosphorylated Ser446.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 297682, 70686, 80824
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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