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Invitrogen™ Phospho-E2F1 (Ser332) Polyclonal Antibody
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Catalog No. PIPA512914
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400 μL
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PIPA512914 400 μL
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Catalog No. PIPA512914 Supplier Invitrogen™ Supplier No. PA512914
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Description

Rabbit Polyclonal Antibody

Phospho-E2F1 (Ser332) Polyclonal Antibody for DB

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-E2F1 (Ser332)
Applications Dot Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene E2F1
Gene Accession No. Q01094
Gene Alias E2F transcription factor 1; E2F1; E2F-1; mKIAA4009; PBR3; PRB-binding protein E2F-1; RBAP1; RBAP-1; RBBP3; RBBP-3; RBP3; Retinoblastoma-associated protein 1; retinoblastoma-binding protein 3; Transcription factor E2F1
Gene Symbols E2F1
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S332 of human E2F1.
Purification Method Antigen Affinity Chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1869
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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