Invitrogen™ Phospho-EEF2 (Tyr443) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105490

Catalog No. PIPA5105490

Description

Antibody detects endogenous levels of EEF2 only when phosphorylated at Tyr443.

Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

Specifications

• Antigen: Phospho-EEF2 (Tyr443)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EEF2
• Gene Alias: EEF2; EEF-2; Ef2; EF-2; Elongation factor 2; elongation factor-2; eukaryotic translation elongation factor 2; I79_013848; polypeptidyl-tRNA translocase; SCA26; zef2
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13629, 1938, 29565
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P05197, P13639, P58252
• Gene Symbols: EEF2
• Immunogen: A synthesized peptide derived from human EEF2(Accession P13639), corresponding to amino acid residues around phosphorylated Tyr443.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov