Invitrogen™ Phospho-eIF2 beta (Ser2) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106170

Catalog No. PIPA5106170

Description

Antibody detects endogenous levels of EIF2S2 only when phosphorylated at Ser2.

Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Phospho-eIF2 beta (Ser2)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EIF2S2
• Gene Alias: 2810026E11Rik; 38kDa; AA408636; AA571381; AA986487; AW822225; D2Ertd303e; EIF2; EIF2B; EIF2BA; EIF2beta; eIF-2-beta; EIF2S2; Eukaryotic translation initiation factor 2 subunit 2; eukaryotic translation initiation factor 2 subunit beta; eukaryotic translation initiation factor 2, subunit 2 (beta); eukaryotic translation initiation factor 2, subunit 2 (beta, 38kDa); eukaryotic translation initiation factor 2, subunit 2 beta; eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa; PPP1R67; protein phosphatase 1, regulatory subunit 67
• Host Species: Rabbit
• Purification Method: sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 296302, 67204, 8894
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P20042, Q99L45
• Gene Symbols: EIF2S2
• Immunogen: A synthesized peptide derived from human EIF2S2(Accession P20042), corresponding to amino acid residues around phosphorylated Ser2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov