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Invitrogen™ Phospho-eIF4A2 (Tyr49) Polyclonal Antibody
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Catalog No. PIPA5105117
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PIPA5105117 100 μL
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Catalog No. PIPA5105117 Supplier Invitrogen™ Supplier No. PA5105117
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of eIF4A2 only when phosphorylated at Tyr49.

eIF4A2 is a 407 amino acid ATP-dependent RNA helicase belonging to the DEAD box helicase family. It contains one helicase ATP-binding domain and a helicase C-terminal domain. eIF4A2, a subunit of the eIF4F complex, acts as a protein-synthesis initiation factor and thus plays an important role in the binding of mRNA to the 43S pre-initiation complex of ribosomes. Human eIF4A2 interacts with the NS5B protein of Hepatitis C virus (HCV) and facilitates the genomic RNA synthesis of NS5B protein by unwinding the secondary structure of the HCV genome. It is ubiquitously expressed in most of normal tissues, but in variable amounts.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-eIF4A2 (Tyr49)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene EIF4A2
Gene Accession No. P10630, Q14240, Q5RKI1
Gene Alias 4833432N07Rik; ATP dependent RNA helicase eIF4A 2; ATP-dependent RNA helicase eIF4A-2; BM-010; DDX2B; Eif4; EIF4A; EIF4A1; EIF4A2; EIF4AII; eIF-4A-II; eIF4A-II; EIF4F; Eukaryotic initiation factor 4A-II; eukaryotic translation initiation factor 4A; eukaryotic translation initiation factor 4A isoform 2; eukaryotic translation initiation factor 4A, isoform 2; eukaryotic translation initiation factor 4A1; eukaryotic translation initiation factor 4A2; hypothetical protein; N-terminally processed; protein synthesis initiation factor 4AII; RCJMB04_14a6; translational eukaryotic inititation factor 4AII
Gene Symbols EIF4A2
Host Species Rabbit
Immunogen A synthesized peptide derived from human EIF4A2(Accession Q14240), corresponding to amino acid residues around phosphorylated Tyr49.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13682, 1974, 303831
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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