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Invitrogen™ Phospho-eIF4E (Ser209) Polyclonal Antibody
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Catalog No. PIPA517919
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100 μL
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PIPA517919 100 μL
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Catalog No. PIPA517919 Supplier Invitrogen™ Supplier No. PA517919
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Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody.

eIF4E is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A, that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-eIF4E (Ser209)
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene Eif4e
Gene Accession No. P06730, P63073, P63074
Gene Alias AUTS19; CBP; EG668879; EIF4E; EIF-4E; EIF4E1; EIF4EL1; Eif4e-ps; EIF4F; eIF-4F 25 kDa subunit; eukaryotic translation initiation factor 4E; eukaryotic translation initiation factor 4E-like 1; eukaryotic translation initiation factor 4E-like protein; eukaryotic translation initiation factor 4-like protein; If4e; MGC111573; mRNA cap-binding protein; OTTHUMP00000219703; OTTHUMP00000219704; OTTHUMP00000219705; translation initiation factor eIF-4E
Gene Symbols Eif4e
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding pSer209 of human eIF4E.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117045, 13684, 1977
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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