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Invitrogen™ Phospho-eNOS (Ser1177) Recombinant Rabbit Monoclonal Antibody (PS01-10)
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Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA549606

Catalog No. FERMA549606


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Description

Description

Sequence Similarities: No Cross with Mouse and Rat. Tissue Specificity: Platelets, placenta, liver and kidney. Positive Control: HAEC serum starved then treated with 100nM Insulin for 1 hour cell lysate, human placenta tissue. Subcellular Location: Cell membrane, Membrane, caveola, Cytoplasm, cytoskeleton, Golgi apparatus. Predicted band size: 133 kDa.

Nitric oxide (NO) is an inorganic, gaseous free radical that carries a variety of messages between cells. Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO. NO production is mediated by members of the nitric oxide synthase (NOS) family. NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) and endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned. All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-eNOS (Ser1177)
Recombinant Monoclonal
1 mg/mL
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
P29474
NOS3
Synthetic phosphopeptide corresponding to residues surrounding Ser1177 of human eNOS.
100 μL
Primary
Human
Antibody
IgG
Immunohistochemistry (Paraffin), Western Blot
PS01-10
Unconjugated
NOS3
2310065A03Rik; cNOS; Constitutive NOS; Ecnos; EC-NOS; endothelial nitric oxide synthase; endothelial nitric oxide synthase 3; endothelial nitric oxide synthase NOS3; endothelial NOS; eNos; e-NOS; nitric oxide synthase; nitric oxide synthase 3; nitric oxide synthase 3 (endothelial cell); nitric oxide synthase 3 transcript variant eNOS-delta20; nitric oxide synthase 3 transcript variant eNOS-delta20-21; nitric oxide synthase 3 transcript variant eNOS-delta21; nitric oxide synthase 3, endothelial cell; nitric oxide synthase, endothelial; NOS; NOS type III; Nos3; Nos-3; NOSIII; OTTHUMP00000213183
Rabbit
Protein A
RUO
4846
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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