Invitrogen™ Phospho-eNOS (Ser1177) Recombinant Rabbit Monoclonal Antibody (PS01-10)

Catalog No.	Quantity
FERMA549606	100 μL

Catalog No. FERMA549606 Supplier Invitrogen™ Supplier No. MA549606

Description

Rabbit Recombinant Monoclonal Antibody

Sequence Similarities: No Cross with Mouse and Rat. Tissue Specificity: Platelets, placenta, liver and kidney. Positive Control: HAEC serum starved then treated with 100nM Insulin for 1 hour cell lysate, human placenta tissue. Subcellular Location: Cell membrane, Membrane, caveola, Cytoplasm, cytoskeleton, Golgi apparatus. Predicted band size: 133 kDa.

Nitric oxide (NO) is an inorganic, gaseous free radical that carries a variety of messages between cells. Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO. NO production is mediated by members of the nitric oxide synthase (NOS) family. NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) and endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned. All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains.

Specifications

• Antigen: Phospho-eNOS (Ser1177)
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Recombinant Monoclonal
• Clone: PS01-10
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene: NOS3
• Gene Accession No.: P29474
• Gene Alias: 2310065A03Rik; cNOS; Constitutive NOS; Ecnos; EC-NOS; endothelial nitric oxide synthase; endothelial nitric oxide synthase 3; endothelial nitric oxide synthase NOS3; endothelial NOS; eNos; e-NOS; nitric oxide synthase; nitric oxide synthase 3; nitric oxide synthase 3 (endothelial cell); nitric oxide synthase 3 transcript variant eNOS-delta20; nitric oxide synthase 3 transcript variant eNOS-delta20-21; nitric oxide synthase 3 transcript variant eNOS-delta21; nitric oxide synthase 3, endothelial cell; nitric oxide synthase, endothelial; NOS; NOS type III; Nos3; Nos-3; NOSIII; OTTHUMP00000213183
• Gene Symbols: NOS3
• Host Species: Rabbit
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Ser1177 of human eNOS.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4846
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG