Phospho-EphA1 (Tyr605) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA5106125

Catalog No. PIPA5106125

Description

Antibody detects endogenous levels of EPHA1 only when phosphorylated at Tyr605.

EphA1 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EphA1 is expressed in some human cancer cell lines and has been implicated in carcinogenesis.

Specifications

• Antigen: Phospho-EphA1 (Tyr605)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPHA1
• Gene Alias: 5730453L17Rik; AL033318; Embryonic stem cell kinase; EPH; EPH receptor A1; EPH tyrosine kinase; EPH tyrosine kinase 1; EPHA1; ephrin receptor EphA1; ephrin type-A receptor 1; EPHT; EPHT1; erythropoietin-producing hepatoma amplified sequence; erythropoietin-producing hepatoma receptor; Esk; hEpha1; mEpha1; MGC163163; oncogene EPH; soluble EPHA1 variant 1; soluble EPHA1 variant 2; tyrosine-protein kinase receptor EPH; Tyrosine-protein kinase receptor ESK
• Host Species: Rabbit
• Purification Method: sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13835, 2041
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P21709, Q60750
• Gene Symbols: EPHA1
• Immunogen: A synthesized peptide derived from human EPHA1(Accession P21709), corresponding to amino acid residues around phosphorylated Tyr605.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG