Invitrogen™ Phospho-EphA2 (Tyr594) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105549

Catalog No. PIPA5105549

Description

Antibody detects endogenous levels of EPHA2 only when phosphorylated at Tyr594.

EPHA2 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. EPHA2 is overexpressed in many types of human cancers. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

Specifications

• Antigen: Phospho-EphA2 (Tyr594)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPHA2
• Gene Alias: ARCC2; AW545284; CTPA; CTPP1; CTRCT6; Eck; EPH receptor A2; Epha2; ephrin receptor EphA2; Ephrin type-A receptor 2; Epithelial cell kinase; epithelial cell receptor protein tyrosine kinase; I79_019726; Myk2; Sek2; Sek-2; soluble EPHA2 variant 1; tyrosine-protein kinase receptor ECK; Tyrosine-protein kinase receptor MPK-5; tyrosine-protein kinase receptor SEK-2
• Host Species: Rabbit
• Purification Method: Sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13836, 1969
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P29317, Q03145
• Gene Symbols: EPHA2
• Immunogen: A synthesized peptide derived from human EPHA2(Accession P29317), corresponding to amino acid residues around phosphorylated Tyr594.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov