Invitrogen™ Phospho-EphA6 (Tyr977) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA564787

Catalog No. PIPA564787

Description

Phospho-EphA6 (Tyr977) Polyclonal Antibody detects endogenous levels of EphA6 only when phosphorylated at Tyr977.

EPHA6 is a member of the ephrin receptor subfamily of protein-tyrosine kinases which have been implicated in axon guidance, neuron-target interactions, regional compartmentalization, and synaptic functions in nervous systems. EPHA6 is highly expressed in the brain and testis. Reduction in EPHA6 has been detected in Hypospadias, a common defect affecting the growth and closure of the external genitalia. Genetic inhibition of EPHA6 in mice produces behavioral deficits specifically in tests of learning and memory. Mice deficient in EPHA6 show reduced memory of the consequences of the training context.

Specifications

• Antigen: Phospho-EphA6 (Tyr977)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Epha6
• Gene Alias: DKFZp434C1418; EHK2; EHK-2; EK12; EPA6; EPH homology kinase 2; Eph receptor A6; EPHA6; EPH-like kinase 12; ephrin receptor EphA6; ephrin type-A receptor 6; FLJ35246; HEK12; m-ehk2; PRO57066; tyrosine-protein kinase receptor EHK-2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13840, 285220, 29202
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P54758, Q62413, Q9UF33
• Gene Symbols: Epha6
• Immunogen: A synthesized peptide derived from human EPHA6 (Phospho-Tyr977).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG