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Invitrogen™ Phospho-EphA6 (Tyr978) Polyclonal Antibody
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Catalog No. PIPA5106130
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100 μL
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PIPA5106130 100 μL
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Catalog No. PIPA5106130 Supplier Invitrogen™ Supplier No. PA5106130
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of EPHA6 only when phosphorylated at Tyr978.

EPHA6 is a member of the ephrin receptor subfamily of protein-tyrosine kinases which have been implicated in axon guidance, neuron-target interactions, regional compartmentalization, and synaptic functions in nervous systems. EPHA6 is highly expressed in the brain and testis. Reduction in EPHA6 has been detected in Hypospadias, a common defect affecting the growth and closure of the external genitalia. Genetic inhibition of EPHA6 in mice produces behavioral deficits specifically in tests of learning and memory. Mice deficient in EPHA6 show reduced memory of the consequences of the training context.
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Specifications

Antigen Phospho-EphA6 (Tyr978)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Epha6
Gene Accession No. P54758, Q62413, Q9UF33
Gene Alias DKFZp434C1418; EHK2; EHK-2; EK12; EPA6; EPH homology kinase 2; Eph receptor A6; EPHA6; EPH-like kinase 12; ephrin receptor EphA6; ephrin type-A receptor 6; FLJ35246; HEK12; m-ehk2; PRO57066; tyrosine-protein kinase receptor EHK-2
Gene Symbols Epha6
Host Species Rabbit
Immunogen A synthesized peptide derived from human EPHA6(Accession Q9UF33), corresponding to amino acid residues around phosphorylated Tyr978.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13840, 285220, 29202
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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