Invitrogen™ Phospho-EphA8 (Tyr839) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105876

Catalog No. PIPA5105876

Description

Antibody detects endogenous levels of EPHA8 only when phosphorylated at Tyr839.

EPHA8 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. EPHA8 plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.

Specifications

• Antigen: Phospho-EphA8 (Tyr839)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Epha8
• Gene Alias: AW047546; Eek; EK3; epa8; EPH- and ELK-related kinase; EPH- and ELK-related tyrosine kinase; Eph receptor A8; Epha8; EPH-like kinase 3; Ephrin type-A receptor 8; Ephrin type-A receptor 8 precursor (Tyrosine-protein kinase receptor EEK) (EPH-and ELK-related kinase); Hek3; hydroxyaryl-protein kinase; KIAA1459; mKIAA1459; protein-tyrosine kinase; tyrosine-protein kinase receptor EEK; tyrosylprotein kinase
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13842, 2046, 60589
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O09127, P29321, P29322
• Gene Symbols: Epha8
• Immunogen: A synthesized peptide derived from human EPHA8(Accession P29322), corresponding to amino acid residues around phosphorylated Tyr839.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov