Invitrogen™ Phospho-EphB Pan (Tyr600, Tyr602, Tyr614, Tyr596) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA564578

Catalog No. PIPA564578

Description

Phospho-EphB Pan (Tyr600, Tyr602, Tyr614, Tyr596) Polyclonal Antibody detects endogenous levels of EphB Pan only when phosphorylated at Tyr600, Tyr602, Tyr614, Tyr596.

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.

Specifications

• Antigen: Phospho-EphB Pan (Tyr600, Tyr602, Tyr614, Tyr596)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ephb1
• Gene Alias: 9330129L11; AI042935; AW456895; AW488255; C130099E04Rik; CAPB; Cek10; Cek5; Cek6; Developmental kinase 2; developmental kinase 5; Developmentally-regulated Eph-related tyrosine kinase; Drt; EK2; EK5; EK6; ELK; Elkh; ELK-related protein tyrosine kinase; elk-related tyrosine kinase; embryonic kinase 2; ENSMUSG00000074119; EPH receptor B1; EPH receptor B2; Eph receptor B2 (ELK-related protein tyrosine kinase); Eph receptor B3; EPH receptor B4; eph tyrosine kinase 2; EPH tyrosine kinase 3; EPHB1; EPHB2; EphB2/CTF1; EphB2/CTF2; Ephb3; Ephb4; EPH-like kinase 2; EPH-like kinase 5; EPH-like kinase 6; EPH-like tyrosine kinase 2; EPH-like tyrosine kinase-2; Ephrin B1; Ephrin B2; Ephrin B3; Ephrin B4; ephrin receptor EphB4; ephrin type-B receptor 1; Ephrin type-B receptor 2; ephrin type-B receptor 3; Ephrin type-B receptor 4; EphrinB1; EphrinB2; EphrinB3; EphrinB4; EPHT2; EPHT3; Epth2; Epth3; ERK; ETECK; ETK2; HEK2; HEK5; Hek6; HEK-6; Hepatoma transmembrane kinase; HTK; human embryo kinase 2; Mdk2; mDK-2; MDK5; mDK-5; MGC87492; Myk1; NET; Neural kinase; neuronally-expressed EPH-related tyrosine kinase; Nuk; nuk receptor tyrosine kinase; PCBC; Prkm5; protein-tyrosine kinase HEK5; Qek5; Renal carcinoma antigen NY-REN-47; RGD1564232; Sek3; Sek4; soluble EPHB1 variant 1; soluble EPHB4 variant 1; soluble EPHB4 variant 2; soluble EPHB4 variant 3; Tyro11; TYRO5; Tyro6; tyrosine kinase MYK-1; Tyrosine-protein kinase receptor EPH-2; tyrosine-protein kinase receptor EPH-3; tyrosine-protein kinase receptor HTK; tyrosine-protein kinase receptor SEK-3; Tyrosine-protein kinase receptor SEK-4; tyrosine-protein kinase TYRO11; Tyrosine-protein kinase TYRO5; tyrosine-protein kinase TYRO6
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13844, 13845, 13846, 2047, 2048, 2049, 2050, 24338, 270190, 287989, 313633, 686310
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P09759, P29323, P54753, P54754, P54760, P54761, P54762, P54763, Q8CBF3
• Gene Symbols: Ephb1, Ephb2, EPHB3, EPHB4
• Immunogen: A synthesized peptide derived from human EPHB1/2/3/4 (Phospho-Tyr600/602/614/596).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG