Invitrogen™ Phospho-EphB1/EphB2/EphB3/EphB4 (Tyr600, Tyr602, Tyr614, Tyr596) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105878

Catalog No. PIPA5105878

Description

Antibody detects endogenous levels of EPHB1/2/3/4 only when phosphorylated at Tyr600/602/614/596.

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.

Specifications

• Antigen: Phospho-EphB1/EphB2/EphB3/EphB4 (Tyr600, Tyr602, Tyr614, Tyr596)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ephb1
• Gene Alias: 9330129L11; AI042935; AW456895; AW488255; C130099E04Rik; CAPB; Cek10; Cek5; Cek6; Developmental kinase 2; developmental kinase 5; Developmentally-regulated Eph-related tyrosine kinase; DRT; EK2; EK5; EK6; ELK; Elkh; ELK-related protein tyrosine kinase; elk-related tyrosine kinase; embryonic kinase 2; ENSMUSG00000074119; EPH receptor B1; Eph receptor B2; Eph receptor B2 (ELK-related protein tyrosine kinase); EPH receptor B3; Eph receptor B4; eph tyrosine kinase 2; EPH tyrosine kinase 3; Ephb1; EPHB2; EphB2/CTF1; EphB2/CTF2; Ephb3; EPHB4; EPH-like kinase 2; EPH-like kinase 5; EPH-like kinase 6; EPH-like tyrosine kinase 2; EPH-like tyrosine kinase-2; ephrin receptor EphB4; ephrin type-B receptor 1; Ephrin type-B receptor 2; ephrin type-B receptor 3; Ephrin type-B receptor 4; EPHT2; EPHT3; Epth2; Epth3; ERK; ETECK; ETK2; HEK2; HEK5; HEK6; hepatoma transmembrane kinase; Htk; human embryo kinase 2; Mdk2; mDK-2; MDK5; mDK-5; MYK1; Net; Neural kinase; neuronally-expressed EPH-related tyrosine kinase; Nuk; nuk receptor tyrosine kinase; PCBC; Prkm5; protein-tyrosine kinase HEK5; Qek5; renal carcinoma antigen NY-REN-47; RGD1564232; Sek3; Sek4; soluble EPHB1 variant 1; soluble EPHB4 variant 1; soluble EPHB4 variant 2; soluble EPHB4 variant 3; Tyro11; TYRO5; Tyro6; Tyrosine kinase MYK-1; tyrosine-protein kinase receptor EPH-2; Tyrosine-protein kinase receptor EPH-3; tyrosine-protein kinase receptor HTK; tyrosine-protein kinase receptor SEK-3; Tyrosine-protein kinase receptor SEK-4; tyrosine-protein kinase TYRO11; Tyrosine-protein kinase TYRO5; tyrosine-protein kinase TYRO6
• Host Species: Rabbit
• Purification Method: Sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13844, 13845, 13846, 2047, 2048, 2049, 2050, 24338, 270190, 287989, 313633, 686310
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P09759, P29323, P54753, P54754, P54760, P54761, P54762, P54763, Q8CBF3
• Gene Symbols: Ephb1, Ephb2, EPHB3, EPHB4
• Immunogen: A synthesized peptide derived from human EPHB1(Accession P54762), corresponding to amino acid residues around phosphorylated Tyr596.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov