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Invitrogen™ Phospho-EphB6 (Tyr645) Polyclonal Antibody
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Catalog No. PIPA5106136
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PIPA5106136 100 μL
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Catalog No. PIPA5106136 Supplier Invitrogen™ Supplier No. PA5106136
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of EPHB6 only when phosphorylated at Tyr645.

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-EphB6 (Tyr645)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene EPHB6
Gene Accession No. O08644, O15197, P0C0K7
Gene Alias Cekl; chicken eph/elk receptor-like protein; EPB6; EPH receptor B6; EPHB6; EphB6v; Epherin B6; Epherin receptor B6; ephrin type A receptor; ephrin type-B receptor 6; HEP; human kinase-defective Eph-family receptor protein; MEP; MGC129910; MGC129911; Tyrosine-protein kinase-defective receptor EPH-6
Gene Symbols EPHB6
Host Species Rabbit
Immunogen A synthesized peptide derived from human EPHB6(Accession O15197), corresponding to amino acid residues around phosphorylated Tyr645.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13848, 2051, 312275
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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