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Phospho-Ephrin B (Tyr329) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985226
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50-198-5226 100 μL
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Catalog No. 50-198-5226 Supplier Bioss Supplier No. BS3217R
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Description

Rabbit Polyclonal Antibody

Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.

Specifications

Antigen Phospho-Ephrin B (Tyr329)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene EFNB1
Gene Accession No. P98172
Gene Alias CEK5 ligand; CEK5 receptor ligand; CEK5-L; CEL5-L; CFND; CFNS; EFB1; EFL3; EFL-3; EFL6; Efnb1; EFNB3; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; ephrin B1; Ephrin B3; EphrinB1; Ephrin-B1; Ephrin-B1 C-terminal fragment; Ephrin-B1 CTF; Ephrin-B1 ICD; Ephrin-B1 intracellular domain; Ephrin-B1 precursor; Epl2; Eplg2; EPLG8; kinase ephrin-B1; LERK2; LERK-2; LERK8; Stimulated by retinoic acid gene 1 protein; Stra1; STRA1 protein
Gene Symbols EFNB1
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human Ephrin B around the phosphorylation site of Tyr329.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1947
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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