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Invitrogen™ Phospho-Ephrin B1/B2/B3 (Tyr324/311/318) Polyclonal Antibody
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Catalog No. PIPA537810
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PIPA537810 100 μL
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Catalog No. PIPA537810 Supplier Invitrogen™ Supplier No. PA537810
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Description

Rabbit Polyclonal Antibody

A suggested positive control for Western blot is K562 cells; suggested positive control for IHC is human brain tissue.

Eph receptors and ephrins exhibit complementary expression in many tissues during embryogenesis indicating that bidirectional activation of Eph receptors and ephrin-B proteins may occur at expression domain interfaces. Ephrin-B1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration. The distribution of ephrin-B1 in the developing retina suggests that it influences retinal axon mapping along the dorsal-ventral axis and may be involved in intratectal development The transmembrane ligand ephrin-B2 and its receptor tyrosine kinase EphB4 are specifically expressed on arterial and venous endothelial cells, respectively.
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Specifications

Antigen Phospho-Ephrin B1/B2/B3 (Tyr324/311/318)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene EFNB3
Gene Accession No. P52799, P98172, Q15768
Gene Alias CEK5 receptor ligand; CEK5-L; CFND; CFNS; EFB1; EFL3; EFL-3; EFL6; EFL-6; Efnb1; Efnb2; EFNB3; Elf2; ELF-2; ELF-3; ELK ligand; Elk-L; ELK-L3; EPH-related receptor transmembrane ligand ELK-L3; EPH-related receptor tyrosine kinase ligand 2; EPH-related receptor tyrosine kinase ligand 5; EPH-related receptor tyrosine kinase ligand 8; ephrin B1; ephrin B2; ephrin B3; ephrin ligand B3; ephrin-B1; Ephrin-B1 C-terminal fragment; Ephrin-B1 CTF; Ephrin-B1 ICD; Ephrin-B1 intracellular domain; Ephrin-B2; ephrin-B2 precursor; ephrin-B3; Epl2; Epl5; Epl8; EPLG2; EPLG5; EPLG8; HTK ligand; HTKL; Htk-L; LERK2; LERK-2; Lerk5; LERK-5; LERK8; LERK-8; ligand of eph-related kinase 5; NLERK-1; NLERK-2; Stimulated by retinoic acid gene 1 protein; Stra1
Gene Symbols EFNB1, EFNB2, EFNB3
Host Species Rabbit
Immunogen Peptide sequence around phosphorylation site of tyrosine 324/311/318 (G-D-Y(p)-G-H) derived from Human Ephrin B1/B2/B3.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1947, 1948, 1949
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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