Invitrogen™ Phospho-Ephrin B1/B2/B3 (Tyr324) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103267

Catalog No. PIPA5103267

Description

Antibody detects endogenous levels of Ephrin B1/B2/B3 only when phosphorylated at Tyr324.

Eph receptors and ephrins exhibit complementary expression in many tissues during embryogenesis indicating that bidirectional activation of Eph receptors and ephrin-B proteins may occur at expression domain interfaces. Ephrin-B1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration. The distribution of ephrin-B1 in the developing retina suggests that it influences retinal axon mapping along the dorsal-ventral axis and may be involved in intratectal development The transmembrane ligand ephrin-B2 and its receptor tyrosine kinase EphB4 are specifically expressed on arterial and venous endothelial cells, respectively.

Specifications

• Antigen: Phospho-Ephrin B1/B2/B3 (Tyr324)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EFNB3
• Gene Alias: CEK5 receptor ligand; CEK5-L; CFND; CFNS; EFB1; EFL3; EFL-3; EFL6; EFL-6; Efnb1; Efnb2; EFNB3; Elf2; ELF-2; ELF-3; ELK ligand; Elk-L; ELK-L3; EPH-related receptor transmembrane ligand ELK-L3; EPH-related receptor tyrosine kinase ligand 2; EPH-related receptor tyrosine kinase ligand 5; EPH-related receptor tyrosine kinase ligand 8; ephrin B1; ephrin B2; ephrin B3; ephrin ligand B3; ephrin-B1; Ephrin-B1 C-terminal fragment; Ephrin-B1 CTF; Ephrin-B1 ICD; Ephrin-B1 intracellular domain; Ephrin-B2; ephrin-B2 precursor; ephrin-B3; Epl2; Epl5; Epl8; EPLG2; EPLG5; EPLG8; HTK ligand; HTKL; Htk-L; LERK2; LERK-2; Lerk5; LERK-5; LERK8; LERK-8; ligand of eph-related kinase 5; NLERK-1; NLERK-2; Stimulated by retinoic acid gene 1 protein; Stra1
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13641, 13642, 13643, 1947, 1948, 1949, 25186, 306636, 360546
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O35393, P52795, P52796, P52799, P52800, P98172, Q15768
• Gene Symbols: EFNB1, EFNB2, EFNB3
• Immunogen: A synthesized peptide derived from human EFNB1(Accession P98172), corresponding to amino acid residues around phosphorylated Tyr324.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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