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Invitrogen™ Phospho-Ephrin B1/B2/B3 (Tyr324) Polyclonal Antibody
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Catalog No. PIPA5103267
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100 μL
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PIPA5103267 100 μL
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Catalog No. PIPA5103267 Supplier Invitrogen™ Supplier No. PA5103267
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Ephrin B1/B2/B3 only when phosphorylated at Tyr324.

Eph receptors and ephrins exhibit complementary expression in many tissues during embryogenesis indicating that bidirectional activation of Eph receptors and ephrin-B proteins may occur at expression domain interfaces. Ephrin-B1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration. The distribution of ephrin-B1 in the developing retina suggests that it influences retinal axon mapping along the dorsal-ventral axis and may be involved in intratectal development The transmembrane ligand ephrin-B2 and its receptor tyrosine kinase EphB4 are specifically expressed on arterial and venous endothelial cells, respectively.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Ephrin B1/B2/B3 (Tyr324)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene EFNB3
Gene Accession No. O35393, P52795, P52796, P52799, P52800, P98172, Q15768
Gene Alias CEK5 receptor ligand; CEK5-L; CFND; CFNS; EFB1; EFL3; EFL-3; EFL6; EFL-6; Efnb1; Efnb2; EFNB3; Elf2; ELF-2; ELF-3; ELK ligand; Elk-L; ELK-L3; EPH-related receptor transmembrane ligand ELK-L3; EPH-related receptor tyrosine kinase ligand 2; EPH-related receptor tyrosine kinase ligand 5; EPH-related receptor tyrosine kinase ligand 8; ephrin B1; ephrin B2; ephrin B3; ephrin ligand B3; ephrin-B1; Ephrin-B1 C-terminal fragment; Ephrin-B1 CTF; Ephrin-B1 ICD; Ephrin-B1 intracellular domain; Ephrin-B2; ephrin-B2 precursor; ephrin-B3; Epl2; Epl5; Epl8; EPLG2; EPLG5; EPLG8; HTK ligand; HTKL; Htk-L; LERK2; LERK-2; Lerk5; LERK-5; LERK8; LERK-8; ligand of eph-related kinase 5; NLERK-1; NLERK-2; Stimulated by retinoic acid gene 1 protein; Stra1
Gene Symbols EFNB1, EFNB2, EFNB3
Host Species Rabbit
Immunogen A synthesized peptide derived from human EFNB1(Accession P98172), corresponding to amino acid residues around phosphorylated Tyr324.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13641, 13642, 13643, 1947, 1948, 1949, 25186, 306636, 360546
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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