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Invitrogen™ Phospho-Ephrin B1 (Tyr317) Polyclonal Antibody
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Catalog No. PIPA536802
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PIPA536802 100 μL
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Catalog No. PIPA536802 Supplier Invitrogen™ Supplier No. PA536802
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 38 and 45 kDa. Purity is >95% by SDS-PAGE.

Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Ephrin B1 (Tyr317)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene EFNB1
Gene Accession No. P52795, P52796, P98172
Gene Alias CEK5 ligand; CEK5 receptor ligand; CEK5-L; CEL5-L; CFND; CFNS; EFB1; EFL3; EFL-3; EFL6; EFNB1; EFNB3; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; ephrin B1; Ephrin B3; EphrinB1; ephrin-B1; Ephrin-B1 C-terminal fragment; Ephrin-B1 CTF; Ephrin-B1 ICD; Ephrin-B1 intracellular domain; Ephrin-B1 precursor; Epl2; EPLG2; EPLG8; kinase ephrin-B1; Lerk2; LERK-2; LERK8; Stimulated by retinoic acid gene 1 protein; Stra1; STRA1 protein; transmembrane ligand
Gene Symbols EFNB1
Host Species Rabbit
Immunogen Synthetic phosphopeptide derived from human Ephrin-B1 around the phosphorylation site of Tyrosine 317.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13641, 1947, 25186
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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