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Invitrogen™ Phospho-EpoR (Tyr368) Polyclonal Antibody
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Catalog No. PIPA5104831
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100 μL
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PIPA5104831 100 μL
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Catalog No. PIPA5104831 Supplier Invitrogen™ Supplier No. PA5104831
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Epo-R only when phosphorylated at Tyrosine 368.

EpoR encodes the erythropoietin receptor, which belongs to the cytokine receptor family. When erythropoietin binds to this receptor, it activates the Jak2 tyrosine kinase, which in turn activates various intracellular pathways including Ras/MAP kinase, phosphatidylinositol 3-kinase, and STAT transcription factors. The stimulated erythropoietin receptor plays a role in the survival of erythroid cells. Defects in this gene may result in erythroleukemia and familial erythrocytosis. Dysregulation of this gene may also affect the growth of certain tumors. Multiple transcript variants are produced as a result of alternate splicing. Diseases associated with EPOR include Erythrocytosis, Familial, 1 and Erythroleukemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-EpoR (Tyr368)
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene EPOR
Gene Accession No. P14753, P19235, Q07303
Gene Alias EPO R; EPOR; EPO-R; Erythropoietin receptor; pEpoR
Gene Symbols EPOR
Host Species Rabbit
Immunogen A synthesized peptide derived from human EPOR(Accession P19235), corresponding to amino acid residues around phosphorylated Tyr368.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13857, 2057, 24336
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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