Phospho-ErbB3 (Tyr1222) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA538499

Catalog No. PIPA538499

Description

c-erbB-3/HER-3 is the third member of the type I family of growth factor receptors. It binds to ligands in the heregulin family. C-erbB-3 is over-expressed in a variety of tumors inculding breast, stomach, pancreas, and colon. Heregulin and EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents.

Specifications

• Antigen: Phospho-ErbB3 (Tyr1222)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ERBB3
• Gene Alias: ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3, proto-oncogene-like protein c-ErbB-3, receptor tyrosine-protein kinase erbB-3, tyrosine kinase-type cell surface receptor HER3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13867, 2065, 29496
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P21860, Q61526, Q62799
• Gene Symbols: ERBB3
• Immunogen: A synthetic phosphopeptide derived from human HER3/ErbB3 around the phosphorylation site of Tyr1222 (L-G-YP-E-Y)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov