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Invitrogen™ Phospho-EZH2 (Thr487) Polyclonal Antibody
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Catalog No. PIPA5105660
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100 μL
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PIPA5105660 100 μL
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Catalog No. PIPA5105660 Supplier Invitrogen™ Supplier No. PA5105660
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of EZH2 only when phosphorylated at Thr487.

EZH2 (Histone-lysine N-methyltransferase) is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems. Mutations affecting EZH2 can cause Weaver syndrome (WVS).
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-EZH2 (Thr487)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene EZH2
Gene Accession No. Q15910, Q61188
Gene Alias an; enhancer of zeste 2 polycomb repressive complex 2 subunit; enhancer of zeste homolog 2; enhancer of zeste homolog 2 (Drosophila); ENX 1; ENX1; Enx-1; Enx1h; EZH 2; EZH1; EZH2; EZH-2; EZH2b; histone-lysine N-methyltransferase EZH2; KMT6; KMT6A; lysine N-methyltransferase 6; mKIAA4065; OTTHUMP00000213774; OTTHUMP00000213778; OTTHUMP00000213779; OTTHUMP00000213780; WVS; WVS2
Gene Symbols EZH2
Host Species Rabbit
Immunogen A synthesized peptide derived from human EZH2(Accession Q15910), corresponding to amino acid residues around phosphorylated Thr487.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14056, 2146, 312299
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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