Invitrogen™ Phospho-Ezrin (Tyr478) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104800

Catalog No. PIPA5104800

Description

Antibody detects endogenous levels of Ezrin only when phosphorylated at Tyrosine 478.

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Specifications

• Antigen: Phospho-Ezrin (Tyr478)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ezr
• Gene Alias: AW146364; CVIL; CVL; Cytovillin; cytovillin 2; DKFZp762H157; epididymis secretory protein Li 105; ezr; ezr.L; ezr.S; EZRI; Ezrin; ezrin L homeolog; ezrin L homeolog; ezrin S homeolog; FLJ26216; HEL-S-105; MGC1584; p81; R75297; VIL2; villin 2; villin 2 (ezrin); villin-2; XELAEV_18027043mg
• Host Species: Rabbit
• Purification Method: sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22350, 54319, 7430
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P15311, P26040, P31977
• Gene Symbols: Ezr
• Immunogen: A synthesized peptide derived from human EZR(Accession P15311), corresponding to amino acid residues around phosphorylated Tyr478.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov