Invitrogen™ Phospho-FANCI (Ser559) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595685

Catalog No. PIPA595685

Description

Antigen Affinity Purified from Pooled Serum.

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms.

Specifications

• Antigen: Phospho-FANCI (Ser559)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FANCI
• Gene Alias: FANCI; Fanconi anemia complementation group I; Fanconi anemia group I protein; Fanconi anemia group I protein homolog; Fanconi anemia, complementation group I; KIAA1794; Protein FACI
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55215
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: ~0.15 mg/mL
• Formulation: 10mM HEPES with 100μg/mL BSA, 50% glycerol, 150mM NaCl and no preservative; pH 7.5
• Gene Accession No.: Q9NVI1
• Gene Symbols: FANCI
• Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser556 conjugated to KLH.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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