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Invitrogen™ Phospho-Fascin (Ser39) Polyclonal Antibody
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Catalog No. PIPA5143700
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100 μL
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PIPA5143700 100 μL
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Catalog No. PIPA5143700 Supplier Invitrogen™ Supplier No. PA5143700
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Description

Rabbit Polyclonal Antibody

This antibody was cross-adsorbed to a phospho-serine peptide before affinity purified using phosho-fascin (Ser-39) peptide (without carrier). The antibody detects a 55 kDa* band corresponding to fascin on SDS-PAGE immunoblots of mouse C2C12 and human HeLa cells treated with Calyculin A. This band is not observed after lambda phosphatase treatment. The antibody also detects fascin (Ser-39) phosphorylation in chick DRG neurons.

Fascin organizes filamentous actin into bundles with a minimum of 4. 1:1 actin/fascin ratio. It is probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Fascin (Ser39)
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration ~0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene FSCN1
Gene Accession No. P85845, Q16658, Q61553
Gene Alias 55 kDa actin-bundling protein; 55kDa actin-bundling protein; AI663989; Fan1; fascin; fascin 1; fascin actin-bundling protein 1; Fascin homolog 1; fascin homolog 1, actin bundling protein; fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus); fascin homolog 1, actin-bundling protein; Fascin1; fascin-1; Fscn1; fscn1 {ECO:0000250; HSN; p55; Singed; Singed (Drosophila) like (sea urchin fascin homolog like); singed-like (fascin homolog, sea urchin); singed-like protein; SNL; UniProtKB:Q16658}
Gene Symbols FSCN1
Host Species Rabbit
Immunogen Fascin (Ser-39) synthetic peptide (coupled to carrier protein) corresponds to amino acids surrounding serine 39 in human fascin. This sequence has high homology to the conserved site in rat and mouse fascin, as well as to the conserved region in fascin-2, but has low homology to the conserved region in fascin-3.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14086, 6624, 683788
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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