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Invitrogen™ Phospho-FEN1 (Ser187) Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA564848
Description
Phospho-FEN1 (Ser187) Polyclonal Antibody detects endogenous levels of FEN1 only when phosphorylated at Ser187.
FEN-1 (Flap Endonuclease and Five prime Exonuclease) is a 42 a protein that functions as an endonuclease that cleaves branched DNA structures containing single-stranded 5' flaps or as an exonuclease on DNA nicks and gaps. FEN-1 endonuclease and exonuclease activities are stimulated by an association with proliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 is believed to have important roles in DNA replication and repair and is required in cell-free DNA replication systems.
Specifications
Phospho-FEN1 (Ser187) | |
Polyclonal | |
Unconjugated | |
FEN1 | |
AW538437; DNase IV; fen1; FEN-1; fen1 {ECO:0000255; FEN-1 {ECO:0000255; Flap endonuclease 1; flap endonuclease 1 {ECO:0000255; flap structure specific endonuclease 1; flap structure-specific endonuclease 1; flap structure-specific endonuclease 1 {ECO:0000255; HAMAP-Rule:MF_03140}; hFEN-1; Maturation factor 1; maturation factor-1; MF1; RAD2 | |
Rabbit | |
Affinity chromatography | |
RUO | |
14156, 2237, 84490 | |
-20°C | |
Liquid |
Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
P39748, P39749, Q5XIP6 | |
FEN1 | |
A synthesized peptide derived from human Rad2/FEN1 (Phospho-Ser187). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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