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Invitrogen™ Phospho-FEN1 (Ser187) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA564848

Catalog No. PIPA564848


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Description

Description

Phospho-FEN1 (Ser187) Polyclonal Antibody detects endogenous levels of FEN1 only when phosphorylated at Ser187.

FEN-1 (Flap Endonuclease and Five prime Exonuclease) is a 42 a protein that functions as an endonuclease that cleaves branched DNA structures containing single-stranded 5' flaps or as an exonuclease on DNA nicks and gaps. FEN-1 endonuclease and exonuclease activities are stimulated by an association with proliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 is believed to have important roles in DNA replication and repair and is required in cell-free DNA replication systems.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-FEN1 (Ser187)
Polyclonal
Unconjugated
FEN1
AW538437; DNase IV; fen1; FEN-1; fen1 {ECO:0000255; FEN-1 {ECO:0000255; Flap endonuclease 1; flap endonuclease 1 {ECO:0000255; flap structure specific endonuclease 1; flap structure-specific endonuclease 1; flap structure-specific endonuclease 1 {ECO:0000255; HAMAP-Rule:MF_03140}; hFEN-1; Maturation factor 1; maturation factor-1; MF1; RAD2
Rabbit
Affinity chromatography
RUO
14156, 2237, 84490
-20°C
Liquid
Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P39748, P39749, Q5XIP6
FEN1
A synthesized peptide derived from human Rad2/FEN1 (Phospho-Ser187).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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