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Invitrogen™ Phospho-FGFR1/FGFR2 (Tyr730, Tyr733) Polyclonal Antibody
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Catalog No. PIPA5105954
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PIPA5105954 100 μL
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Catalog No. PIPA5105954 Supplier Invitrogen™ Supplier No. PA5105954
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of FGFR1/2 only when phosphorylated at Tyr730/733.

FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-FGFR1/FGFR2 (Tyr730, Tyr733)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene FGFR1
Gene Accession No. P11362, P16092, P21802, P21803, Q04589
Gene Alias AU043015; AW208770; AW556123; bacteria-expressed kinase; basic fibroblast growth factor receptor 1; BBDS; BEK; BEK fibroblast growth factor receptor; BFGFR; bFGF-R; bFGF-R-1; BFR-1; CD331; CD332; CEK; CEK3; CFD1; c-fgr; Eask; ECCL; ECT1; FGF Receptor 2; FGF receptor-1; FGFBR; fgfr 1; Fgfr1; Fgfr-1; FGFR1/PLAG1 fusion; FGFR2; Fgfr-2; Fgfr7; Fgfr-7; Fibroblast growth factor receptor 1; fibroblast growth factor receptor 2; FLG; FLT2; FLT-2; Fms-like tyrosine kinase 2; fms-related tyrosine kinase 2; HBGFR; heparin-binding growth factor receptor; HH2; HRTFDS; Hspy; hydroxyaryl-protein kinase; JWS; KAL2; Keratinocyte growth factor receptor; KGFR; KGFRTr; KSAM; K-SAM; MFR; N-sam; OGD; protein tyrosine kinase, receptor like 14; proto-oncogene c-Fgr; Soluble KGFR; svs; TK14; TK25
Gene Symbols FGFR1, FGFR2
Host Species Rabbit
Immunogen A synthesized peptide derived from human FGFR1(Accession P11362), corresponding to amino acid residues around phosphorylated Tyr730.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14182, 14183, 2260, 2263, 25022, 79114
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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