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Phospho-FGFR3 (Tyr724) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982672
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50-198-2672 100 μL
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Catalog No. 50-198-2672 Supplier Bioss Supplier No. BS13170R
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Description

Rabbit Polyclonal Antibody

This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described.

Specifications

Antigen Phospho-FGFR3 (Tyr724)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene FGFR3
Gene Accession No. P22607
Gene Alias ACH; CD333; CEK2; FGFR3; FGFR-3; FGFR3deltaTM; Fibroblast growth factor receptor 3; fibroblast growth factor receptor 3 variant 4; Flg-2; FR3; HBGFR; heparin-binding growth factor receptor; HSFGFR3EX; hydroxyaryl-protein kinase; JTK4; Mfr3; sam3; tyrosine kinase JTK4
Gene Symbols FGFR3
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human FGFR3 around the phosphorylation site of Tyr724.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2261
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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