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Invitrogen™ Phospho-FGFR4 (Tyr754) Polyclonal Antibody
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Catalog No. PIPA5105882
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100 μL
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PIPA5105882 100 μL
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Catalog No. PIPA5105882 Supplier Invitrogen™ Supplier No. PA5105882
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of FGFR4 only when phosphorylated at Tyr754.

FGFR4 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. FGFR4 is required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. FGFR4 plays a role in postnatal lung development and may be involved in the development of skeletal muscle cell lineages.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-FGFR4 (Tyr754)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Fgfr4
Gene Accession No. P22455, Q03142, Q498D6
Gene Alias CD334; CTLA-2-beta protein; FGF Receptor; FGF Receptor 4; FGFR; Fgfr4; FGFR-4; Fibroblast growth factor receptor 4; fibroblast growth factor receptor 4 16 minus form; hydroxyaryl-protein kinase; JTK2; MGC20292; Mpk-11; protein-tyrosine kinase; protein-tyrosine kinase receptor MPK-11; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase
Gene Symbols Fgfr4
Host Species Rabbit
Immunogen A synthesized peptide derived from human FGFR4(Accession P22455), corresponding to amino acid residues around phosphorylated Tyr754.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14186, 2264, 25114
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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