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Invitrogen™ Phospho-FMRP (Ser499) Polyclonal Antibody
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Catalog No. PIPA535389
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PIPA535389 100 μL
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Catalog No. PIPA535389 Supplier Invitrogen™ Supplier No. PA535389
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Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine, canine, chicken, human, mouse, non-human primate, sheep, Xenopus and zebrafish based on 100% sequence homology. This antibody contains enough material to conduct 10 mini-Western blots.

FMR1 binds RNA and is associated with polysomes. The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure. Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-FMRP (Ser499)
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 0.1mg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene FMR1
Gene Accession No. P35922, Q06787, Q80WE1
Gene Alias AT24755; BcDNA:GM08679; cg 6203 gene product from transcript cg6203-rc; cg6203; CG6203-PA; CG6203-PB; CG6203-PC; CG6203-PD; CG6203-PE; CG6203-PF; CG6203-PG; CG6203-PH; CG6203-PI; CG6203-PJ; CG6203-PK; dFMR; DFmr1; dFmrp; dfxr; dfxr1; dFXRP; Dmel\CG6203; Dmel_CG6203; dmfr1; drosophila fragile X mental retardation protein; EP(3)3517; FMR; FMR1; Fmr-1; Fmr1-PA; Fmr1-PB; Fmr1-PC; Fmr1-PD; Fmr1-PE; Fmr1-PF; Fmr1-PG; Fmr1-PH; Fmr1-PI; Fmr1-PJ; Fmr1-PK; FMRP; FMRP translational regulator 1; fragile X; fragile X mental retardation; fragile X mental retardation 1; fragile X mental retardation gene; fragile X mental retardation protein; fragile X mental retardation protein 1; Fragile X mental retardation protein 1 homolog; fragile X mental retardation related 1; fragile X mental retardation syndrome 1; fragile X mental retardation syndrome 1 homolog; Fragile X mental retardation syndrome-related protein 1; fragile X mental retardation-1 protein; fragile X protein; fragile x related; fragile X related protein; fragile X retardation 1 protein; fragile X-related; fragile-X; Fragile-X mental retardation 1; Fragile-X mental retardation protein; Fragile-X-related; FRAXA; FXR; MGC87458; POF; POF1; protein FMR-1; ragile X mental retardation protein; synaptic functional regulator FMR1
Gene Symbols FMR1
Host Species Rabbit
Immunogen Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser499 of rat FMR1 conjugated to KLH.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14265, 2332, 24948, 422395
Target Species Human, Mouse, Rat, Chicken
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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