Phospho-FRA1 (Ser265) Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS3158R

Catalog No. 50-198-5187

Description

The v-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. Members of the c-Fos gene family, including c-Fos, Fos B, Fra-1 and Fra-2, encode nuclear phosphoproteins that are rapidly and transiently induced by a variety of agents and function as transcriptional regulators for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers that bind to specific DNA response elements, c-Fos proteins are only active as heterodimers with members of the Jun gene family. In addition, selected ATF/CREB family members can form leucine zipper dimers with Fos and Jun. Different dimers exhibit differential specificity and affinity for AP-1 and CRE sites.

Specifications

• Antigen: Phospho-FRA1 (Ser265)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FOSL1
• Gene Alias: AW538199; BOS_24884; FOS like 1, AP-1 trancription factor subunit; FOS like 1, AP-1 transcription factor subunit; FOS like antigen 1; Fosl1; FOS-like antigen 1; fos-like antigen 1-like; FOS-like antigen-1; Fos-related antigen 1; FRA; Fra1; FRA-1; HGNC:13718; LOC100338208; LOW QUALITY PROTEIN: fos-related antigen 1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 8061
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: P15407
• Gene Symbols: FOSL1
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human FRA1 around the phosphorylation site of Ser265.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG