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Invitrogen™ Phospho-Fra1 (Thr227) Polyclonal Antibody
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Catalog No. PIPA5105504
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PIPA5105504 100 μL
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Catalog No. PIPA5105504 Supplier Invitrogen™ Supplier No. PA5105504
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of FRA1 only when phosphorylated at Thr227.

The v-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. Members of the c-Fos gene family, including c-Fos, Fos B, Fra-1 and Fra-2, encode nuclear phosphoproteins that are rapidly and transiently induced by a variety of agents and function as transcriptional regulators for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers that bind to specific DNA response elements, c-Fos proteins are only active as heterodimers with members of the Jun gene family. In addition, selected ATF/CREB family members can form leucine zipper dimers with Fos and Jun. Different dimers exhibit differential specificity and affinity for AP-1 and CRE sites.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Fra1 (Thr227)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene FOSL1
Gene Accession No. P10158, P15407, P48755
Gene Alias AW538199; FOS like 1, AP-1 trancription factor subunit; FOS like 1, AP-1 transcription factor subunit; FOS like antigen 1; Fosl1; FOS-like antigen 1; FOS-like antigen-1; fos-related antigen 1; FRA; Fra1; fra-1; HGNC:13718; LOW QUALITY PROTEIN: fos-related antigen 1
Gene Symbols FOSL1
Host Species Rabbit
Immunogen A synthesized peptide derived from human FOSL1(Accession P15407), corresponding to amino acid residues around phosphorylated Thr227.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14283, 25445, 8061
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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