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Invitrogen™ Phospho-FRS2 (Tyr436) Polyclonal Antibody
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Catalog No. PIPA537785
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100 μL
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PIPA537785 100 μL
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Catalog No. PIPA537785 Supplier Invitrogen™ Supplier No. PA537785
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Description

Rabbit Polyclonal Antibody

A suggested positive control for Western blot is HUVEC or JK cells; suggested positive control for IHC is human brain tissue.

Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-FRS2 (Tyr436)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene FRS2
Gene Accession No. Q8WU20
Gene Alias 4732458E18; C330018A15Rik; FGFR signalling adaptor; FGFR substrate 2; FGFR-signaling adaptor SNT; fibroblast growth factor receptor substrate 2; FRS1A; FRS2; Frs2a; FRS2alpha; FRS2-alpha; SNT; SNT1; SNT-1; SNT2; suc1-associated neurotrophic factor target 1
Gene Symbols FRS2
Host Species Rabbit
Immunogen Peptide sequence around phosphorylation site of tyrosine 436(L-N-Y(p)-I-Q) derived from Human FRS2.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10818
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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