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Invitrogen™ Phospho-FRS2 (Tyr436) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537785

Catalog No. PIPA537785


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Description

Description

A suggested positive control for Western blot is HUVEC or JK cells; suggested positive control for IHC is human brain tissue.

Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. [UniProt].
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-FRS2 (Tyr436)
Polyclonal
Unconjugated
FRS2
4732458E18; C330018A15Rik; FGFR signalling adaptor; FGFR substrate 2; FGFR-signaling adaptor SNT; fibroblast growth factor receptor substrate 2; FRS1A; FRS2; Frs2a; FRS2alpha; FRS2-alpha; SNT; SNT1; SNT-1; SNT2; suc1-associated neurotrophic factor target 1
Rabbit
Affinity chromatography
RUO
10818
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q8WU20
FRS2
Peptide sequence around phosphorylation site of tyrosine 436(L-N-Y(p)-I-Q) derived from Human FRS2.
100 μL
Primary
Human
Antibody
IgG
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