Invitrogen™ Phospho-FRS2 (Tyr436) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537785

Catalog No. PIPA537785

Description

A suggested positive control for Western blot is HUVEC or JK cells; suggested positive control for IHC is human brain tissue.

Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. [UniProt].

Specifications

• Antigen: Phospho-FRS2 (Tyr436)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FRS2
• Gene Alias: 4732458E18; C330018A15Rik; FGFR signalling adaptor; FGFR substrate 2; FGFR-signaling adaptor SNT; fibroblast growth factor receptor substrate 2; FRS1A; FRS2; Frs2a; FRS2alpha; FRS2-alpha; SNT; SNT1; SNT-1; SNT2; suc1-associated neurotrophic factor target 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10818
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8WU20
• Gene Symbols: FRS2
• Immunogen: Peptide sequence around phosphorylation site of tyrosine 436(L-N-Y(p)-I-Q) derived from Human FRS2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG