Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Invitrogen™ Phospho-FRS2 (Tyr436) Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA537785
Description
A suggested positive control for Western blot is HUVEC or JK cells; suggested positive control for IHC is human brain tissue.
Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. [UniProt].
Specifications
Phospho-FRS2 (Tyr436) | |
Polyclonal | |
Unconjugated | |
FRS2 | |
4732458E18; C330018A15Rik; FGFR signalling adaptor; FGFR substrate 2; FGFR-signaling adaptor SNT; fibroblast growth factor receptor substrate 2; FRS1A; FRS2; Frs2a; FRS2alpha; FRS2-alpha; SNT; SNT1; SNT-1; SNT2; suc1-associated neurotrophic factor target 1 | |
Rabbit | |
Affinity chromatography | |
RUO | |
10818 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
Q8WU20 | |
FRS2 | |
Peptide sequence around phosphorylation site of tyrosine 436(L-N-Y(p)-I-Q) derived from Human FRS2. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction