Invitrogen™ Phospho-Fumarase (Thr236) Polyclonal Antibody

Catalog No.	Quantity
PIPA567505	100 μL

Catalog No. PIPA567505 Supplier Invitrogen™ Supplier No. PA567505

Description

Rabbit Polyclonal Antibody

Predicted to react with Mouse and Rat samples.

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.

Specifications

• Antigen: Phospho-Fumarase (Thr236)
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: FH
• Gene Accession No.: P07954, P14408, P97807
• Gene Alias: EF-3; Fh; Fh1; Fh-1; FMRD; fumarase; fumarate hydratase; fumarate hydratase 1; fumarate hydratase, mitochondrial; HLRCC; LRCC; MCL; MCUL1
• Gene Symbols: FH, Fh1
• Host Species: Rabbit
• Immunogen: Synthesized peptide sequence derived from Human Fumarase around phosphorylation site of threonine 236(T-H-T(p)-Q-D).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 14193, 14194, 2271, 24368
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov