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Invitrogen™ Phospho-GAB2 (Tyr643) Polyclonal Antibody
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Catalog No. PIPA537778
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100 μL
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PIPA537778 100 μL
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Catalog No. PIPA537778 Supplier Invitrogen™ Supplier No. PA537778
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Description

Rabbit Polyclonal Antibody

A suggested positive control for Western blot is NIH-3T3 cells; suggested positive control for IHC is human brain tissue.

This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-GAB2 (Tyr643)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene GAB2
Gene Accession No. Q9EQH1, Q9UQC2, Q9Z1S8
Gene Alias AI463667; D130058I17Rik; GAB2; Grb2 associated binder 2; GRB2 associated binding protein 2; GRB2-associated binder 2; GRB2-associated binding protein 2; GRB2-associated-binding protein 2; GRB3-3; Growth factor receptor bound protein 2-associated protein 2; KIAA0571; p97; PH domain-containing adaptor molecule p97; pp100
Gene Symbols GAB2
Host Species Rabbit
Immunogen Peptide sequence around phosphorylation site of tyrosine 643(V-D-Y(p)-V-Q) derived from Human Gab2.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14389, 84477, 9846
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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