Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA14729

Invitrogen™ Phospho-GABBR1 (Ser923) Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA14729
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA14729 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA14729 Supplier Invitrogen™ Supplier No. PA14729
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine, human, mouse and non-human primate based on 100% sequence homology. This antibody detects a band at ~102 kDa, representing GABAb R1 protein phosphorylated at Ser923.

Receptor for GABA. The activity of this receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipids hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA-B-R inhibit neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA-B-R decrease neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-GABBR1 (Ser923)
Applications Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene GABBR1
Gene Accession No. Q9WV18, Q9Z0U4
Gene Alias bM573K1.1; bM573K1.1.1 (gamma-aminobutyric acid (GABA) B receptor, 1a); DAAP-188P13.3; dJ271M21.1.1; dJ271M21.1.2; FLJ92613; GABA(B) receptor; GABAB; GABA-B receptor 1; GABA-B receptor, R1 subunit; GABAB1; Gaba-b1; GABAbR1; GABA-BR1; GABA-B-R1; Gababr1 receptor; Gaba-b-r1a; Gaba-br1a receptor; GABA-BR1b receptor; Gabbr1; GABBR1-3; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) B receptor 1; gamma-aminobutyric acid (GABA) B receptor, 1; gamma-aminobutyric acid (GABA-B) receptor, 1; gamma-aminobutyric acid type B receptor subunit 1; GB1; GBR1; GPRC3A; HGB1a; OTTHUMP00000109099; OTTHUMP00000214725; seven transmembrane helix receptor
Gene Symbols GABBR1
Host Species Rabbit
Immunogen Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser923 of rat GABBR1 conjugated to KLH.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54393, 81657
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.