Invitrogen™ Phospho-GAP43 (Ser41) Polyclonal Antibody

Catalog No.	Quantity
PA14626	100 μL

Catalog No. PA14626 Supplier Invitrogen™ Supplier No. PA14626

Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine, canine, chicken, finch, human, mouse, non-human primate, Xenopus and zebrafish based on 100% sequence homology. This antibody is specific for the ~50 kDa Gap-43 protein phosphorylated at Ser41 in Western blots of rat brain lysate. In some tissues the antibody also recognizes a higher molecular weight protein, that is also recognized by the Pan Gap-43 antibody, that may be a Gap-43 aggregate or oligomer. Immunolabeling blocked by the phosphopeptide used as the antigen but not by the corresponding dephosphopeptide.

GAP43 (Neuromodulin) is associated with nerve growth. GAP43 is expressed by developing and regenerating neurons, and to a lesser extent reactive glial cells. It is a major component of the motile 'growth cones' that form the tips of elongating axons. GAP43 also plays a role in axonal and dendritic filopodia induction.

Specifications

• Antigen: Phospho-GAP43 (Ser41)
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.25 mg/mL
• Conjugate: Unconjugated
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
• Gene: GAP43
• Gene Accession No.: P06837, P07936
• Gene Alias: Axonal membrane protein GAP-43; B-50; Basp2; brain abundant, membrane attached signal protein 2; calmodulin-binding protein P-57; Gap43; GAP-43; growth accentuating protein 43; growth associated protein 43; growth-associated protein 43; MGC156666; nerve growth-related peptide GAP43; neural phosphoprotein B-50; Neuromodulin; neuron growth-associated protein 43; neuron protein F1; PP46; Protein F1
• Gene Symbols: GAP43
• Host Species: Rabbit
• Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser41 of rat GAP43 conjugated to KLH.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 14432, 29423
• Target Species: Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG