Invitrogen™ Phospho-GCN2 (Thr899) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105886

Catalog No. PIPA5105886

Description

Antibody detects endogenous levels of GCN2 only when phosphorylated at Thr899.

EIF2AK4 (GCN2) is a metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor-2 in response to low amino acid availability. It plays a role as an activator of the integrated stress response required for adapatation to amino acid starvation. Mutations in the gene lead to pulmonary vennocclusive disease 2.

Specifications

• Antigen: Phospho-GCN2 (Thr899)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EIF2AK4
• Gene Alias: 2610011M03; EIF2AK4; eIF-2-alpha kinase GCN2; eukaryotic translation initiation factor 2 alpha kinase 4; eukaryotic translation initiation factor 2-alpha kinase 4; Gcn2; GCN2 eIF2alpha kinase; GCN2-like protein; general control nonderepressible 2; Kiaa1338; mGCN2; PVOD2
• Host Species: Rabbit
• Purification Method: sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114859, 27103, 440275
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: D4A7V9, Q9P2K8, Q9QZ05
• Gene Symbols: EIF2AK4
• Immunogen: A synthesized peptide derived from human EIF2AK4(Accession Q9P2K8), corresponding to amino acid residues around phosphorylated Thr899.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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