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Invitrogen™ Phospho-GCN2 (Thr899) Polyclonal Antibody
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Catalog No. PIPA5105886
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100 μL
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PIPA5105886 100 μL
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Catalog No. PIPA5105886 Supplier Invitrogen™ Supplier No. PA5105886
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of GCN2 only when phosphorylated at Thr899.

EIF2AK4 (GCN2) is a metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor-2 in response to low amino acid availability. It plays a role as an activator of the integrated stress response required for adapatation to amino acid starvation. Mutations in the gene lead to pulmonary vennocclusive disease 2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-GCN2 (Thr899)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene EIF2AK4
Gene Accession No. D4A7V9, Q9P2K8, Q9QZ05
Gene Alias 2610011M03; EIF2AK4; eIF-2-alpha kinase GCN2; eukaryotic translation initiation factor 2 alpha kinase 4; eukaryotic translation initiation factor 2-alpha kinase 4; Gcn2; GCN2 eIF2alpha kinase; GCN2-like protein; general control nonderepressible 2; Kiaa1338; mGCN2; PVOD2
Gene Symbols EIF2AK4
Host Species Rabbit
Immunogen A synthesized peptide derived from human EIF2AK4(Accession Q9P2K8), corresponding to amino acid residues around phosphorylated Thr899.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114859, 27103, 440275
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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