Phospho-GEF H1 (Ser886) Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS2201R

Catalog No. 50-198-4575

Description

GEF-H1 activates Rho GTPases by promoting the exchange of GDP and GTP. Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. GEF-H1 may be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: Phospho-GEF H1 (Ser886)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ARHGEF2
• Gene Alias: AA408978; Arhgef2; CG10188; CG10188 gene product from transcript CG10188-RB; CG10188-PA; CG10188-PB; CG10188-PC; DKFZp547L106; DKFZp547P1516; Dmel\CG10188; Dmel_CG10188; FLJ45440; GEF; GEFH1; GEF-H1; Guanine nucleotide exchange factor H1; KIAA0651; Lbcl1; LBC′S first cousin; Lfc; LFP40; Lymphoid blast crisis-like 1; Microtubule-regulated Rho-GEF; mKIAA0651; Oncogene LFC; OTTHUMP00000018855; P40; Proliferating cell nucleolar antigen p40; Rho guanine nucleotide exchange factor 2; rho guanine nucleotide exchange factor 2-like protein; Rho/Rac guanine nucleotide exchange factor (GEF) 2; Rho/Rac guanine nucleotide exchange factor 2; Rhobin; uncharacterized protein
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 9181
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q92974
• Gene Symbols: ARHGEF2
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human Arhgef2 around the phosphorylation site of Ser886.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG