Invitrogen™ Phospho-GKAP1 (Ser25) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105217

Catalog No. PIPA5105217

Description

Antibody detects endogenous levels of GKAP only when phosphorylated at Ser25.

The approximately 142 kDa Tankyrase protein is ubiquitously expressed in mammalian cells and is localized to human telomeres. It has homology to ankyrins and to the catalytic domain of poly (adenosine diphosphate-ribose) polymerase (PARP). Tankyrase binds to TRF1 (telomeric repeat binding factor-1), which negatively regulates the maintenance of telomere length.

Specifications

• Antigen: Phospho-GKAP1 (Ser25)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gkap1
• Gene Alias: 42 kD cGMP-dependent protein kinase anchoring protein; 42kDa; 4933400B15Rik; cGMP-dependent protein kinase anchoring protein; cGMP-dependent protein kinase anchoring protein 42kDa; cGMP-dependent protein kinase-anchoring protein of 42 kDa; D13Ertd340e; FKSG21; G kinase anchoring protein 1; G kinase-anchoring protein 1; GKAP1; Gkap42; protein kinase anchoring protein GKAP42
• Host Species: Rabbit
• Purification Method: sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 361202, 56278, 80318
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q5VSY0, Q5XIG5, Q9JMB0
• Gene Symbols: Gkap1
• Immunogen: A synthesized peptide derived from human GKAP1(Accession Q5VSY0), corresponding to amino acid residues around phosphorylated Ser25.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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