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Invitrogen™ Phospho-GLI2 (Ser234) Polyclonal Antibody
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Catalog No. PIPA5105347
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100 μL
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PIPA5105347 100 μL
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Catalog No. PIPA5105347 Supplier Invitrogen™ Supplier No. PA5105347
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Gli2 only when phosphorylated at Ser234.

Gli-2 belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-GLI2 (Ser234)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene GLI2
Gene Accession No. P10070
Gene Alias AW546128; CJS; GLI family zinc finger 2; GLI family zinc finger protein 2; GLI2; GLI-Kruppel family member GLI2; glioma-associated oncogene family zinc finger 2; HPE9; oncogene GLI2; PHS2; Tax helper protein; tax helper protein 1; tax helper protein 2; tax-responsive element-2 holding protein; tax-responsive element-25-bp sequence binding protein; Thp; THP1; THP2; zinc finger protein GLI2
Gene Symbols GLI2
Host Species Rabbit
Immunogen A synthesized peptide derived from human GLI2(Accession P10070), corresponding to amino acid residues around phosphorylated Ser234.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2736
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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