Invitrogen™ Phospho-HAND1 (Ser98) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105803

Catalog No. PIPA5105803

Description

Antibody detects endogenous levels of HAND1 only when phosphorylated at Ser98.

HAND1 belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.

Specifications

• Antigen: Phospho-HAND1 (Ser98)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HAND1
• Gene Alias: bHLHa27; Class A basic helix-loop-helix protein 27; eHAND; Ehand1; extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1; HAND1; heart and neural crest derivatives expressed 1; heart and neural crest derivatives expressed transcript 1; heart- and neural crest derivatives-expressed protein 1; Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast; Hxt; Th1; Thing1; thing-1
• Host Species: Rabbit
• Purification Method: sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15110, 59112, 9421
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O96004, P97832, Q64279
• Gene Symbols: HAND1
• Immunogen: A synthesized peptide derived from human HAND1(Accession O96004), corresponding to amino acid residues around phosphorylated Ser98.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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