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Invitrogen™ Phospho-HDAC5/HDAC9 (Ser259, Ser220) Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA540215
Description
This antibody is predicted to react with mouse based on sequence homology.
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
Specifications
Phospho-HDAC5/HDAC9 (Ser259, Ser220) | |
Polyclonal | |
Unconjugated | |
HDAC9 | |
Antigen NY-CO-9; HD5; HD7; HD7b; HD9; HDAC; HDAC5; HDAC7; HDAC7B; HDAC9; hdac-9; HDAC9B; HDAC9FL; HDRP; histone deacetylase 4/5-related protein; histone deacetylase 5; Histone deacetylase 7B; histone deacetylase 9; Histone deacetylase-related protein; KIAA0600; KIAA0744; MEF-2 interacting transcription repressor (MITR) protein; MEF2-interacting transcription repressor MITR; MITR; NY-CO-9 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
10014, 15184, 79221, 9734 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Immunohistochemistry, Western Blot | |
1 mg/mL | |
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
Q99N13, Q9UKV0, Q9UQL6, Q9Z2V6 | |
HDAC5, HDAC9 | |
Synthesized peptide derived from human HDAC5/9 around the phosphorylation site of S259/220. | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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