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Invitrogen™ Phospho-HDAC5 (Ser498) Polyclonal Antibody
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Catalog No. PIPA537779
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100 μL
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PIPA537779 100 μL
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Catalog No. PIPA537779 Supplier Invitrogen™ Supplier No. PA537779
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Description

Rabbit Polyclonal Antibody

A suggested positive control for Western blot is 293 cells; suggested positive control for IHC is human breast carcinoma. The homology between synthetic peptide sequence and rat is 100% .

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-HDAC5 (Ser498)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.02% sodium azide; pH 7.4
Gene HDAC5
Gene Accession No. Q9UQL6, Q9Z2V6
Gene Alias AI426555; Antigen NY-CO-9; DKFZp779K1053; FLJ90614; HD5; HD7; HD7b; HD9; HDAC; Hdac4; HDAC5; HDAC-5; HDAC7; HDAC7B; HDAC9; HDAC9B; HDAC9FL; HDRP; histone deacetylase 4; histone deacetylase 5; histone deacetylase mHDA1; KIAA0600; KIAA0744; mHDA1; mKIAA0600; NY-CO-9
Gene Symbols HDAC5
Host Species Rabbit
Immunogen Peptide sequence around phosphorylation site of serine 498 (T-Q-S(p)-S-P) derived from Human HDAC5/7.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10014, 15184
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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