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Invitrogen™ Phospho-HDAC6 (Ser22) Polyclonal Antibody
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Catalog No. PIPA5105035
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PIPA5105035 100 μL
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Catalog No. PIPA5105035 Supplier Invitrogen™ Supplier No. PA5105035
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of HDAC6 only when phosphorylated at Serine 22.

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-HDAC6 (Ser22)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene HDAC6
Gene Accession No. Q9UBN7, Q9Z2V5
Gene Alias CPBHM; FLJ16239; Hd6; HDA6; Hdac5; Hdac6; histone deacetylase 5; histone deacetylase 6; Histone deacetylase mHDA2; JM21; KIAA0901; mHDA2; PPP1R90; protein phosphatase 1, regulatory subunit 90; scurfy candidate 6; Sfc6
Gene Symbols HDAC6
Host Species Rabbit
Immunogen A synthesized peptide derived from human HDAC6(Accession Q9UBN7), corresponding to amino acid residues around phosphorylated Ser22.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10013, 15185
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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