Invitrogen™ Phospho-HDAC7 (Ser486) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106090

Catalog No. PIPA5106090

Description

Antibody detects endogenous levels of HDAC7 only when phosphorylated at Ser486.

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Phospho-HDAC7 (Ser486)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HDAC7
• Gene Alias: 5830434K02Rik; HD7; HD7a; hdac4l; Hdac7; hdac-7; Hdac7a; histone deacetylase 7; Histone deacetylase 7A; mFLJ00062
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51564, 56233
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8C2B3, Q8WUI4
• Gene Symbols: HDAC7
• Immunogen: A synthesized peptide derived from human HDAC7(Accession Q8WUI4), corresponding to amino acid residues around phosphorylated Ser486.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG