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Invitrogen™ Phospho-HEC1 (Ser165) Polyclonal Antibody
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Catalog No. PIPA534978
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100 μL
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PIPA534978 100 μL
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Catalog No. PIPA534978 Supplier Invitrogen™ Supplier No. PA534978
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Rabbit Polyclonal Antibody

Recommended positive controls: HeLa, Blocking peptide (GTX70013-PEP). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Hec1 is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-HEC1 (Ser165)
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.127 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene NDC80
Gene Accession No. O14777, Q9D0F1
Gene Alias 2610020P18Rik; AV139730; HEC; HEC1; HEC-1; HEC2; HEC4; Highly expressed in cancer protein; highly expressed in cancer, rich in leucine heptad repeats; HsHec1; hsNDC80; kinetochore associated 2; kinetochore protein Hec1; Kinetochore protein NDC80 homolog; kinetochore-associated protein 2; KNTC2; NDC80; NDC80 homolog, kinetochore complex component; NDC80 homolog, kinetochore complex component (S. cerevisiae); NDC80 kinetochore complex component; NDC80 kinetochore complex component homolog; NDC80, kinetochore complex component; putative kinetochore protein NDC80 like protein; retinoblastoma-associated protein HEC; TID3
Gene Symbols NDC80
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to the amino acids around Ser 165 conjugated to KLH.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10403, 301701, 67052
Target Species Human, Mouse, Rodent, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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