Invitrogen™ Phospho-Histone H2A (Ser139) Monoclonal Antibody (GT1021)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531471

Catalog No. PIMA531471

Description

Keep as concentrated solution. Positive Control: HCT116 (30 μM Cisplatin treatment for 24hr). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: Phospho-Histone H2A (Ser139)
• Classification: Monoclonal
• Concentration: 1.05 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: C0HKE1, C0HKE3, C0HKE4, C0HKE5, C0HKE6, P04908, P0C0S5, P0C0S6, P0C0S8, P16104, P20671, P27661, Q8CGP6, Q96A08, Q96KK5, Q96QV6, Q99878
• Gene Symbols: H2ac1, H2AC11, H2AC12, H2AC13, H2AC14, H2AC4, H2AC7, H2AC8, H2AFX, H2AX, H2AZ1, H2bc1
• Immunogen: Carrier-protein conjugated synthetic peptide surrounding phospho Ser139 of human Histone H2A.X. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot, Immunocytochemistry
• Clone: GT1021
• Conjugate: Unconjugated
• Gene: H2AC11
• Gene Alias: 1190022L06; Acetyl-Histone H2; AW228881; dJ160A22.4; dJ86C11.1; gammaH2ax; H2A; H2A 615 antibody; H2A GL101 antibody; H2A histone; H2A histone family member; H2A histone family member X; H2A histone family member Z; H2A histone family member Z L homeolog; H2A histone family, member A; H2A histone family, member C; H2A histone family, member E; H2A histone family, member G; H2A histone family, member M; H2A histone family, member P; H2A histone family, member Q; H2A histone family, member V; H2A histone family, member X; H2A histone family, member Z; H2A.1; H2A.1 antibody; H2A.1b; H2A.2; H2A.3; H2a.x; H2A.Z; H2A.Z1; H2a.z-1; H2A.Zl; h2a.zl1; h2a.zl2; H2A/a; H2A/c; H2A/d; H2A/E; H2A/g; H2A/m; H2A/p; H2A/q; H2A/S; H2A/X; H2A/z; H2a-291A; H2a-53; h2a-A; H2AC11; H2AC13; H2AC15; H2AC16; H2AC17; h2ad; H2ae; H2AFA; H2AFALii; H2AFC; H2AFD; H2AFE; H2AFG; H2AFI; H2AFM; H2AFN; H2AFP; H2AFQ; H2AFV; H2afx; H2afz; h2afz.L; H2AG; H2A-GL101; H2AH; h2ai; H2A-III; H2ak; H2AK5ac; H2AX; H2AX histone; H2Az; H2AZ histone; HIS; HIST1H2A3; Hist1h2aa; Hist1h2ab; Hist1h2ac; Hist1h2ad; HIST1H2AE; HIST1H2AE antibody; HIST1H2AG; Hist1h2ah; HIST1H2AI; HIST1H2AJ; HIST1H2AK; HIST1H2AL; HIST1H2AM; Hist1h2an; Hist1h2ao; Hist1h2ap; Hist1h2ba; hist2h2ab; hist2h2ab.S; HIST2H2AC; HIST3H2A; Hist5-2ax; histone 1, H2ab; histone 1, H2ad; histone 1, H2ae; histone 1, H2ag; histone 1, H2ah; histone 1, H2ai; histone 1, H2aj; histone 1, H2ba; histone 2, H2ac; histone 2, H2ai; histone 5 protein 2ax; histone cluster 1, H2A, III (similar to human histone cluster 2, class H2A, member C); histone cluster 1, H2aa; histone cluster 1, H2ab; histone cluster 1, H2ad; histone cluster 1, H2ae; histone cluster 1, H2ag; histone cluster 1, H2ah; histone cluster 1, H2ai; histone cluster 1, H2aj; histone cluster 1, H2ba; histone cluster 2, H2ab S homeolog; histone cluster 2, H2ac; histone H2A; histone H2A type 1; Histone H2A type 1-B; Histone H2A type 1-B/E; Histone H2A type 1-C; Histone H2A type 1-D; Histone H2A type 1-E; Histone H2A type 1-G; Histone H2A type 1-H; Histone H2A type 1-I; Histone H2A type 1-J; Histone H2A type 1-N; Histone H2A type 1-O; Histone H2A type 1-P; Histone H2A type 2-C; histone H2A type 4; Histone H2A, testis; Histone H2A.2; Histone H2A.3; histone H2A.x; Histone H2A.Z; histone H2A.Zl2; histone H2A.Z-like; histone H2A/a; Histone H2A/e; Histone H2A/g; histone H2A/m; histone H2A/p; Histone H2A/ptl; Histone H2A/q; histone H2A/s; histone H2AD; histone H2AE; histone H2A-GL101; histone H2A-III; histone H2A-IV; histone H2AX; Histone H2B type 1-A; histone H2B, testis; histone IIa; hypothetical protein; LOC680322; MGC74460 antibody; pH2A/f; RCJMB04_2h11; RGD1562827; RGD1566119; similar to Histone H2A type 1; testis-specific histone 2a; testis-specific histone 2b; testis-specific histone H2B; TH2A; Th2b; XELAEV_18004421mg; XELAEV_18005732mg; XH2AX; XH2AZ
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 15270, 221613, 255626, 3012, 3013, 3014, 3015, 319165, 319166, 319167, 319168, 319172, 319174, 319191, 51788, 8329, 8331, 8335, 85235, 8969
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid